SOME PATHOLOGICAL ASPECTS OF RAW LIMA BEAN (Phaseolus lunatus Linn. FEEDING TO GROWING

Some pathological changes: accompanying raw lima bean (RLB) feeding to growing rats were investigated. Among the gross patholo­gical observations severe pancreatic hypertrophy and spleen atrophy. The rela­tive weight of liver was significantly (P< 0M5) decreased while kidney 0.05) increas­ed. relative heart unaffected. At necropsy, small intestine fed 40% RLB aoove dilated filed with light-yellow gassy liquid. Histopathologically, livers above showed focuses coagulative necrosis marked congestion hepatic sinusoids centrolobular veins. depletion lymphoid follicles medullary' sinu­soids. There evidence conges­tion renal blood vessels in high diets. No lesions observed tissues. morphology intestinal apicalmicrovilli generally disrupted. They appeared stunted fragmented especially above. Mononuclei cell infilterate characterized lamina propria api Large inte­stinal rnicrovilli. microvilli abnormalities detected 100% cooked (control) diet.